| Manchester United FC | 2:1 | Liverpool FC |
| 14', 24' M. Rashford | 66' E. Bailly(OG) | |
| Everton FC | 2:0 | Brighton & Hove Albion FC |
| 60' G. Song(OG) 76' C. Tosun | ||
| Huddersfield Town AFC | 0:0 | Swansea City AFC |
| Newcastle United FC | 3:0 | Southampton FC |
| 2', 29' Kenedy 57' M. Ritchie | ||
| West Bromwich Albion FC | 1:4 | Leicester City FC |
| 8' S. Rondón | 21' J. Vardy 62' R. Mahrez 76' K. Iheanacho 90'+3 V. Iborra | |
| West Ham United FC | 0:3 | Burnley FC |
| 66' A. Barnes 70', 81' C. Wood | ||
| Chelsea FC | 2:1 | Crystal Palace FC |
| 25' Willian 32' M. Kelly(OG) | 90' P. van Aanholt |
| Arsenal FC | 3:0 | Watford FC |
| 8' S. Mustafi 59' P. Aubameyang 77' H. Mkhitaryan |
||
| AFC Bournemouth | 1:4 | Tottenham Hotspur FC |
| 7' J. Stanislas | 35' D. Alli 62', 87' Son Heung-min 90'+1 S. Aurier |
| Stoke City FC | 0:2 | Manchester City FC |
| 10', 50' D. Silva |
