14 October 2017:
FC Utrecht 3:1 sc Heerenveen
[26' Y. Ayoub, 41', 63' J. Bahebeck - 23' S. Schaars]
Feyenoord Rotterdam 0:0 PEC Zwolle
SV Roda JC Kerkrade 1:0 NAC Breda
[90'+1 A. Auassar]
AFC Ajax 4:0 Sparta Rotterdam
[39' R. Sanusi(OG), 64' S. Floranus(OG), 73' David Neres, 76' A. Younes]
15 October 2017:
HFC ADO Den Haag 1:2 SBV Excelsior Rotterdam
[32' S. Becker - 7' J. Caenepeel, 81' H. Faik]
Willem II Tilburg 3:1 FC Twente
[45'+1, 90'+1 F. Sol, 60' I. Azzaoui - 40' O. Assaidi]
VVV-Venlo 2:5 PSV
[40' C. Leemans, 48' T. Hunte - 23' J. Locadia, 58', 85' G. Pereiro, 67' D. Schwaab, 72' Mauro Júnior]
FC Groningen 1:1 AZ
[53' M. Mahi - 45'+1 A. Jahanbakhsh]
Heracles Almelo 1:1 SBV Vitesse
[73' K. Peterson - 87' B. Linssen]
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